DJ Khaled wants to shout from the rooftops about the benefits of the new Wegovy pill. The “We The Best” rapper/producer is one of several stars who will appear in a 90-second Super Bowl LX commercial on Sunday (Feb. 8) during the big game touting the benefits of the GLP-1 weight loss medication in its new form.

In the spot, Saturday Night Live iron man Kenan Thompson stands atop a water tower in the middle of a lush field to announce some exciting news. “Wegovy now comes in a pill,” says Thompson, as the always excitable Khaled shouts up to him from the ground. “So adults with obesity can lose weight and keep it off along with diet and exercise!”

“Yes, thank you DJ Khaled,” Thompson says, adding, “be honest, if there was a pill that made other healthful things possible, you’d take it.”

The spot — cued to rapper Skee-Lo’s 1995 classic “I Wish” — features a series of other stars humorously describing other useful pills that they would totally take, including actor John C. Reilly wishing for a pill that would help him parallel park and an animal print singlet-wearing Khaled wishing for a pill that could make him a pro wrestler. Peacemaker star Danielle Brooks pines for one that would help her rescue more kittens from trees, as she stretches her arms and hands a cat to movie tough guy Danny Trejo and former SNL player Ana Gasteyer dreaming of a pill that would make people “less judgy about how to lose weight.”

The ad is the first-ever one featuring Novo Nordisk’s new once-daily Wegovy 25mg tablets, with the spot introducing the anticipated pill while taking on popular public perceptions that taking the highly popular new weight loss meds is “the easy way out,” according to a statement. Instead, it stresses that adults with obesity can lose weight using the Wegovy pill, along with diet and exercise.

In a statement, Khaled said, “I know what it’s like to go hard in the gym, eat clean, stay disciplined – put in that work every single day, but still not see the results you want. I knew I wanted to work with Novo Nordisk because I’m a father, I’m a husband, and I want to be the best for my family. When you’re trying to reach your goals and you’re looking for something more, having an option like Wegovy® pill – that’s powerful.”

Super Bowl LX will take place at Levi’s Stadium in Santa Clara, Calif. on Sunday (Feb. 8) and air on NBC, with coverage beginning at 1 p.m. ET.

Check out the ad here.

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